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Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol

INTRODUCTION: Targeted therapy directed at specific molecular alterations is already creating a shift in the treatment of cancer patients. Malignant gliomas commonly overexpress the oncogenes EGFR and PDGFR and contain mutations and deletions of the tumor suppressor genes PTEN and TP53. Some of thes...

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Detalles Bibliográficos
Autores principales:	Fonseca, Clovis Orlando da, Linden, Rafael, Futuro, Débora, Gattass, Cerli Rocha, Quirico-Santos, Thereza
Formato:	Texto
Lenguaje:	English
Publicado:	Birkhäuser-Verlag 2008
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778682/ https://www.ncbi.nlm.nih.gov/pubmed/18726148 http://dx.doi.org/10.1007/s00005-008-0027-0

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