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Monocyte urokinase-type plasminogen activator up-regulation reduces thrombus size in a model of venous thrombosis

BACKGROUND: Our previous studies showed that the direct injection of an adenovirus construct expressing urokinase-type plasminogen activator (uPA) into experimental venous thrombi significantly reduces thrombus weight. The systemic use of adenovirus vectors is limited by inherent hepatic tropism and...

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Detalles Bibliográficos
Autores principales:	Humphries, Julia, Gossage, James A., Modarai, Bijan, Burnand, Kevin G., Sisson, Thomas H., Murdoch, Colin, Smith, Alberto
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier 2009
Materias:	Basic Research Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778796/ https://www.ncbi.nlm.nih.gov/pubmed/19703758 http://dx.doi.org/10.1016/j.jvs.2009.06.047

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