Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis

CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+ CD57+ T cells in a young patient...

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Detalles Bibliográficos
Autores principales: García-Muñoz, R., Rodríguez-Otero, P., Galar, A., Merino, J., Beunza, J. J., Páramo, J. A., Lecumberri, R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778835/
https://www.ncbi.nlm.nih.gov/pubmed/19946421
http://dx.doi.org/10.1155/2009/173439
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author García-Muñoz, R.
Rodríguez-Otero, P.
Galar, A.
Merino, J.
Beunza, J. J.
Páramo, J. A.
Lecumberri, R.
author_facet García-Muñoz, R.
Rodríguez-Otero, P.
Galar, A.
Merino, J.
Beunza, J. J.
Páramo, J. A.
Lecumberri, R.
author_sort García-Muñoz, R.
collection PubMed
description CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+ CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+ CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues.
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spelling pubmed-27788352009-11-24 Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis García-Muñoz, R. Rodríguez-Otero, P. Galar, A. Merino, J. Beunza, J. J. Páramo, J. A. Lecumberri, R. Adv Hematol Case Report CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+ CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+ CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues. Hindawi Publishing Corporation 2009 2009-09-14 /pmc/articles/PMC2778835/ /pubmed/19946421 http://dx.doi.org/10.1155/2009/173439 Text en Copyright © 2009 R. García-Muñoz et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
García-Muñoz, R.
Rodríguez-Otero, P.
Galar, A.
Merino, J.
Beunza, J. J.
Páramo, J. A.
Lecumberri, R.
Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_full Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_fullStr Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_full_unstemmed Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_short Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
title_sort expansion of cd8+cd57+ t cells in an immunocompetent patient with acute toxoplasmosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778835/
https://www.ncbi.nlm.nih.gov/pubmed/19946421
http://dx.doi.org/10.1155/2009/173439
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