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Large-scale insertional mutagenesis of a coleopteran stored grain pest, the red flour beetle Tribolium castaneum, identifies embryonic lethal mutations and enhancer traps

BACKGROUND: Given its sequenced genome and efficient systemic RNA interference response, the red flour beetle Tribolium castaneum is a model organism well suited for reverse genetics. Even so, there is a pressing need for forward genetic analysis to escape the bias inherent in candidate gene approac...

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Detalles Bibliográficos
Autores principales: Trauner, Jochen, Schinko, Johannes, Lorenzen, Marcé D, Shippy, Teresa D, Wimmer, Ernst A, Beeman, Richard W, Klingler, Martin, Bucher, Gregor, Brown, Susan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779179/
https://www.ncbi.nlm.nih.gov/pubmed/19891766
http://dx.doi.org/10.1186/1741-7007-7-73