ALDH1A2 (RALDH2) genetic variation in human congenital heart disease

BACKGROUND: Signaling by the vitamin A-derived morphogen retinoic acid (RA) is required at multiple steps of cardiac development. Since conversion of retinaldehyde to RA by retinaldehyde dehydrogenase type II (ALDH1A2, a.k.a RALDH2) is critical for cardiac development, we screened patients with cong...

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Detalles Bibliográficos
Autores principales: Pavan, Marilene, Ruiz, Viviane F, Silva, Fábio A, Sobreira, Tiago J, Cravo, Roberta M, Vasconcelos, Michelle, Marques, Lívia P, Mesquita, Sonia MF, Krieger, José E, Lopes, Antônio AB, Oliveira, Paulo S, Pereira, Alexandre C, Xavier-Neto, José
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779186/
https://www.ncbi.nlm.nih.gov/pubmed/19886994
http://dx.doi.org/10.1186/1471-2350-10-113

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