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Progranulin is expressed within motor neurons and promotes neuronal cell survival

BACKGROUND: Progranulin is a secreted high molecular weight growth factor bearing seven and one half copies of the cysteine-rich granulin-epithelin motif. While inappropriate over-expression of the progranulin gene has been associated with many cancers, haploinsufficiency leads to atrophy of the fro...

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Detalles Bibliográficos
Autores principales:	Ryan, Cara L, Baranowski, David C, Chitramuthu, Babykumari P, Malik, Suneil, Li, Zhi, Cao, Mingju, Minotti, Sandra, Durham, Heather D, Kay, Denis G, Shaw, Christopher A, Bennett, Hugh PJ, Bateman, Andrew
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779192/ https://www.ncbi.nlm.nih.gov/pubmed/19860916 http://dx.doi.org/10.1186/1471-2202-10-130

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