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Cohesinopathy mutations disrupt the subnuclear organization of chromatin

In Saccharomyces cerevisiae, chromatin is spatially organized within the nucleus with centromeres clustering near the spindle pole body, telomeres clustering into foci at the nuclear periphery, ribosomal DNA repeats localizing within a single nucleolus, and transfer RNA (tRNA) genes present in an ad...

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Detalles Bibliográficos
Autores principales: Gard, Scarlett, Light, William, Xiong, Bo, Bose, Tania, McNairn, Adrian J., Harris, Bethany, Fleharty, Brian, Seidel, Chris, Brickner, Jason H., Gerton, Jennifer L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779225/
https://www.ncbi.nlm.nih.gov/pubmed/19948494
http://dx.doi.org/10.1083/jcb.200906075