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Cohesinopathy mutations disrupt the subnuclear organization of chromatin
In Saccharomyces cerevisiae, chromatin is spatially organized within the nucleus with centromeres clustering near the spindle pole body, telomeres clustering into foci at the nuclear periphery, ribosomal DNA repeats localizing within a single nucleolus, and transfer RNA (tRNA) genes present in an ad...
Autores principales: | Gard, Scarlett, Light, William, Xiong, Bo, Bose, Tania, McNairn, Adrian J., Harris, Bethany, Fleharty, Brian, Seidel, Chris, Brickner, Jason H., Gerton, Jennifer L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779225/ https://www.ncbi.nlm.nih.gov/pubmed/19948494 http://dx.doi.org/10.1083/jcb.200906075 |
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