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Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

The function of primary cilia depends critically on the localization of specific proteins in the ciliary membrane. A major challenge in the field is to understand protein trafficking to cilia. The Hedgehog (Hh) pathway protein Smoothened (Smo), a 7-pass transmembrane protein, moves to cilia when a l...

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Detalles Bibliográficos
Autores principales: Milenkovic, Ljiljana, Scott, Matthew P., Rohatgi, Rajat
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779247/
https://www.ncbi.nlm.nih.gov/pubmed/19948480
http://dx.doi.org/10.1083/jcb.200907126