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Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
The function of primary cilia depends critically on the localization of specific proteins in the ciliary membrane. A major challenge in the field is to understand protein trafficking to cilia. The Hedgehog (Hh) pathway protein Smoothened (Smo), a 7-pass transmembrane protein, moves to cilia when a l...
Autores principales: | Milenkovic, Ljiljana, Scott, Matthew P., Rohatgi, Rajat |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779247/ https://www.ncbi.nlm.nih.gov/pubmed/19948480 http://dx.doi.org/10.1083/jcb.200907126 |
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