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Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease

Chylothorax is a rare but serious postoperative condition with a high rate of morbidity that may lead to death of children with congenital heart disease. Here we reviewed nine consecutive cases with chylothorax in infants and children following cardiac surgery from March 2002 to February 2003. Somat...

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Autores principales: Lim, Kyoung Ah, Kim, Sung Hye, Huh, June, Kang, I-Seok, Lee, Heung Jae, Jun, Tae-Gook, Park, Pyo Won
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779324/
https://www.ncbi.nlm.nih.gov/pubmed/16361802
http://dx.doi.org/10.3346/jkms.2005.20.6.947
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author Lim, Kyoung Ah
Kim, Sung Hye
Huh, June
Kang, I-Seok
Lee, Heung Jae
Jun, Tae-Gook
Park, Pyo Won
author_facet Lim, Kyoung Ah
Kim, Sung Hye
Huh, June
Kang, I-Seok
Lee, Heung Jae
Jun, Tae-Gook
Park, Pyo Won
author_sort Lim, Kyoung Ah
collection PubMed
description Chylothorax is a rare but serious postoperative condition with a high rate of morbidity that may lead to death of children with congenital heart disease. Here we reviewed nine consecutive cases with chylothorax in infants and children following cardiac surgery from March 2002 to February 2003. Somatostatin was added to conservative treatment proctocol to increase effectiveness of therapy in all cases. The duration of somatostatin therapy varied from 7 to 32 days. All cases of chylothorax were successfully treated with intravenous infusion of somatostatin as an adjunctive treatment. Even though two cases showed rebound phenomena, we avoided any surgical procedure in the nine patients who treated with conservative management combined with somatostatin. No significant side effects of somatostatin were observed. It seems that somatostatin is effective, noninvasive and safe therapeutic modality. It can be used as an adjunctive treatment to conservative management to control postoperative chylothorax in children with congenital heart disease.
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spelling pubmed-27793242009-11-20 Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease Lim, Kyoung Ah Kim, Sung Hye Huh, June Kang, I-Seok Lee, Heung Jae Jun, Tae-Gook Park, Pyo Won J Korean Med Sci Original Article Chylothorax is a rare but serious postoperative condition with a high rate of morbidity that may lead to death of children with congenital heart disease. Here we reviewed nine consecutive cases with chylothorax in infants and children following cardiac surgery from March 2002 to February 2003. Somatostatin was added to conservative treatment proctocol to increase effectiveness of therapy in all cases. The duration of somatostatin therapy varied from 7 to 32 days. All cases of chylothorax were successfully treated with intravenous infusion of somatostatin as an adjunctive treatment. Even though two cases showed rebound phenomena, we avoided any surgical procedure in the nine patients who treated with conservative management combined with somatostatin. No significant side effects of somatostatin were observed. It seems that somatostatin is effective, noninvasive and safe therapeutic modality. It can be used as an adjunctive treatment to conservative management to control postoperative chylothorax in children with congenital heart disease. The Korean Academy of Medical Sciences 2005-12 2005-12-31 /pmc/articles/PMC2779324/ /pubmed/16361802 http://dx.doi.org/10.3346/jkms.2005.20.6.947 Text en Copyright © 2005 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lim, Kyoung Ah
Kim, Sung Hye
Huh, June
Kang, I-Seok
Lee, Heung Jae
Jun, Tae-Gook
Park, Pyo Won
Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title_full Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title_fullStr Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title_full_unstemmed Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title_short Somatostatin for Postoperative Chylothorax after Surgery for Children with Congenital Heart Disease
title_sort somatostatin for postoperative chylothorax after surgery for children with congenital heart disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779324/
https://www.ncbi.nlm.nih.gov/pubmed/16361802
http://dx.doi.org/10.3346/jkms.2005.20.6.947
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