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Interleukin-10 Promoter Polymorphism is Associated with the Predisposition to the Development of IgA Nephropathy and Focal Segmental Glomerulosclerosis in Korea

The roles of interleukin-10 (IL-10) have been emphasized in several models of glomerulonephritis (GN). Three biallelic polymorphisms within the IL-10 promoter region, at positions -1,082, -819, and -592 from the transcription initiation site, were shown to affect the level of IL-10 production. To in...

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Detalles Bibliográficos
Autores principales: Chin, Ho Jun, Na, Ki Young, Kim, Soo Jin, Oh, Kook-Hwan, Kim, Yon Su, Lim, Chun Soo, Kim, Suhnggwon, Chae, Dong-Wan
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779332/
https://www.ncbi.nlm.nih.gov/pubmed/16361810
http://dx.doi.org/10.3346/jkms.2005.20.6.989