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Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2

The p90 ribosomal protein kinase 2 (RSK2) is a highly expressed Ser/Thr kinase activated by growth factors and is involved in cancer cell proliferation and tumor promoter-induced cell transformation. RSK2 possesses two non-identical kinase domains, and the structure of its N-terminal domain (NTD), w...

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Detalles Bibliográficos
Autores principales:	Malakhova, Margarita, Kurinov, Igor, Liu, Kangdong, Zheng, Duo, D'Angelo, Igor, Shim, Jung-Hyun, Steinman, Valerie, Bode, Ann M., Dong, Zigang
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779450/ https://www.ncbi.nlm.nih.gov/pubmed/19956600 http://dx.doi.org/10.1371/journal.pone.0008044

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