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Single-molecule imaging of DNA curtains reveals intrinsic energy landscapes for nucleosome deposition

Here we use single-molecule imaging to determine coarse-grained intrinsic energy landscapes for nucleosome deposition on model DNA substrates. Our results reveal distributions that are correlated with recent in silico predictions, reinforcing the hypothesis that DNA contains some intrinsic positioni...

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Detalles Bibliográficos
Autores principales: Visnapuu, Mari-Liis, Greene, Eric C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779460/
https://www.ncbi.nlm.nih.gov/pubmed/19734899
http://dx.doi.org/10.1038/nsmb.1655