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SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks

The gene mutated in Bloom's syndrome, BLM, is important in the repair of damaged replication forks, and it has both pro- and anti-recombinogenic roles in homologous recombination (HR). At damaged forks, BLM interacts with RAD51 recombinase, the essential enzyme in HR that catalyzes homology-dep...

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Detalles Bibliográficos
Autores principales:	Ouyang, Karen J., Woo, Leslie L., Zhu, Jianmei, Huo, Dezheng, Matunis, Michael J., Ellis, Nathan A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779653/ https://www.ncbi.nlm.nih.gov/pubmed/19956565 http://dx.doi.org/10.1371/journal.pbio.1000252

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