Pd/C-Mediated synthesis of indoles in water

We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the...

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Detalles Bibliográficos
Autores principales: Layek, Mohosin, Lakshmi, Udaya, Kalita, Dipak, Barange, Deepak Kumar, Islam, Aminul, Mukkanti, K, Pal, Manojit
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779661/
https://www.ncbi.nlm.nih.gov/pubmed/19936266
http://dx.doi.org/10.3762/bjoc.5.46
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author Layek, Mohosin
Lakshmi, Udaya
Kalita, Dipak
Barange, Deepak Kumar
Islam, Aminul
Mukkanti, K
Pal, Manojit
author_facet Layek, Mohosin
Lakshmi, Udaya
Kalita, Dipak
Barange, Deepak Kumar
Islam, Aminul
Mukkanti, K
Pal, Manojit
author_sort Layek, Mohosin
collection PubMed
description We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the Pd/C-mediated coupling reaction.
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spelling pubmed-27796612009-11-20 Pd/C-Mediated synthesis of indoles in water Layek, Mohosin Lakshmi, Udaya Kalita, Dipak Barange, Deepak Kumar Islam, Aminul Mukkanti, K Pal, Manojit Beilstein J Org Chem Full Research Paper We describe the utility of a Pd/C-Cu mediated method in the synthesis of 2,5-disubstituted indoles in water via a coupling-cyclization strategy. Further application of this methodology has been demonstrated in the preparation of a target indole derivative via a 7-step process the key step being the Pd/C-mediated coupling reaction. Beilstein-Institut 2009-09-23 /pmc/articles/PMC2779661/ /pubmed/19936266 http://dx.doi.org/10.3762/bjoc.5.46 Text en Copyright © 2009, Layek et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Layek, Mohosin
Lakshmi, Udaya
Kalita, Dipak
Barange, Deepak Kumar
Islam, Aminul
Mukkanti, K
Pal, Manojit
Pd/C-Mediated synthesis of indoles in water
title Pd/C-Mediated synthesis of indoles in water
title_full Pd/C-Mediated synthesis of indoles in water
title_fullStr Pd/C-Mediated synthesis of indoles in water
title_full_unstemmed Pd/C-Mediated synthesis of indoles in water
title_short Pd/C-Mediated synthesis of indoles in water
title_sort pd/c-mediated synthesis of indoles in water
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779661/
https://www.ncbi.nlm.nih.gov/pubmed/19936266
http://dx.doi.org/10.3762/bjoc.5.46
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