INTS6/DICE1 inhibits growth of human androgen-independent prostate cancer cells by altering the cell cycle profile and Wnt signaling

BACKGROUND: The gene encoding integrator complex subunit 6 (INTS6), previously known as deleted in cancer cells 1 (DICE1, OMIM 604331) was found to be frequently affected by allelic deletion and promoter hypermethylation in prostate cancer specimens and cell lines. A missense mutation has been detec...

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Detalles Bibliográficos
Autores principales: Filleur, Stephanie, Hirsch, Jennifer, Wille, Aline, Schön, Margarete, Sell, Christian, Shearer, Michael H, Nelius, Thomas, Wieland, Ilse
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Primary research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779787/
https://www.ncbi.nlm.nih.gov/pubmed/19906297
http://dx.doi.org/10.1186/1475-2867-9-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779787/
https://www.ncbi.nlm.nih.gov/pubmed/19906297
http://dx.doi.org/10.1186/1475-2867-9-28

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