Detrusor underactivity: To tone or not to tone the bladder?

OBJECTIVES: The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity. MATERIALS & METHODS: We searched all relevant data from Medline and peer-reviewed journals available online on the...

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Detalles Bibliográficos
Autores principales: Krishnamoorthy, Sriram, Kekre, Nitin S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Evidence Based Urology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779972/
https://www.ncbi.nlm.nih.gov/pubmed/19881143
http://dx.doi.org/10.4103/0970-1591.56186
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author Krishnamoorthy, Sriram
Kekre, Nitin S.
author_facet Krishnamoorthy, Sriram
Kekre, Nitin S.
author_sort Krishnamoorthy, Sriram
collection PubMed
description OBJECTIVES: The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity. MATERIALS & METHODS: We searched all relevant data from Medline and peer-reviewed journals available online on the use of bethanechol in patients with detrusor underactivity. RESULTS: Most reports that suggest a therapeutic clinical benefit with use of bethanechol have all been anecdotal reports and there is no definite clinical evidence available till date to support its clinical usefulness. CONCLUSION: The current available data have shown to offer no definite benefit with the use of parasympathomimetic agents in patients with DU. One of the meta-analysis has shown bethanechol to be ineffective in promoting bladder emptying.
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spelling pubmed-27799722009-11-27 Detrusor underactivity: To tone or not to tone the bladder? Krishnamoorthy, Sriram Kekre, Nitin S. Indian J Urol Evidence Based Urology OBJECTIVES: The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity. MATERIALS & METHODS: We searched all relevant data from Medline and peer-reviewed journals available online on the use of bethanechol in patients with detrusor underactivity. RESULTS: Most reports that suggest a therapeutic clinical benefit with use of bethanechol have all been anecdotal reports and there is no definite clinical evidence available till date to support its clinical usefulness. CONCLUSION: The current available data have shown to offer no definite benefit with the use of parasympathomimetic agents in patients with DU. One of the meta-analysis has shown bethanechol to be ineffective in promoting bladder emptying. Medknow Publications 2009 /pmc/articles/PMC2779972/ /pubmed/19881143 http://dx.doi.org/10.4103/0970-1591.56186 Text en © Indian Journal of Urology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Evidence Based Urology
Krishnamoorthy, Sriram
Kekre, Nitin S.
Detrusor underactivity: To tone or not to tone the bladder?
title Detrusor underactivity: To tone or not to tone the bladder?
title_full Detrusor underactivity: To tone or not to tone the bladder?
title_fullStr Detrusor underactivity: To tone or not to tone the bladder?
title_full_unstemmed Detrusor underactivity: To tone or not to tone the bladder?
title_short Detrusor underactivity: To tone or not to tone the bladder?
title_sort detrusor underactivity: to tone or not to tone the bladder?
topic Evidence Based Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779972/
https://www.ncbi.nlm.nih.gov/pubmed/19881143
http://dx.doi.org/10.4103/0970-1591.56186
work_keys_str_mv AT krishnamoorthysriram detrusorunderactivitytotoneornottotonethebladder
AT kekrenitins detrusorunderactivitytotoneornottotonethebladder

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