A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity

BACKGROUND: Based on its role in angiogenesis and apoptosis, the inhibition of NFκB activity is considered an effective treatment for cancer, hampered by the lack of selective and safe inhibitors. We recently demonstrated that the RH domain of GRK5 (GRK5-RH) inhibits NFκB, thus we evaluated its effe...

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Detalles Bibliográficos
Autores principales: Sorriento, Daniela, Campanile, Alfonso, Santulli, Gaetano, Leggiero, Eleonora, Pastore, Lucio, Trimarco, Bruno, Iaccarino, Guido
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780391/
https://www.ncbi.nlm.nih.gov/pubmed/19900276
http://dx.doi.org/10.1186/1476-4598-8-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780391/
https://www.ncbi.nlm.nih.gov/pubmed/19900276
http://dx.doi.org/10.1186/1476-4598-8-97

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