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A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity
BACKGROUND: Based on its role in angiogenesis and apoptosis, the inhibition of NFκB activity is considered an effective treatment for cancer, hampered by the lack of selective and safe inhibitors. We recently demonstrated that the RH domain of GRK5 (GRK5-RH) inhibits NFκB, thus we evaluated its effe...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780391/ https://www.ncbi.nlm.nih.gov/pubmed/19900276 http://dx.doi.org/10.1186/1476-4598-8-97 |