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Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

BACKGROUND: Protein kinase C interacting protein (PKCI/HINT1) is a small protein belonging to the histidine triad (HIT) family proteins. Its brain immunoreactivity is located in neurons and neuronal processes. PKCI/HINT1 gene knockout (KO) mice display hyper-locomotion in response to D-amphetamine w...

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Detalles Bibliográficos
Autores principales: Barbier, Elisabeth, Wang, Jia Bei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780446/
https://www.ncbi.nlm.nih.gov/pubmed/19912621
http://dx.doi.org/10.1186/1471-2202-10-132