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Delayed onset of the diurnal melatonin rise in patients with Huntington’s disease

Sleep disturbances are very prevalent in Huntington’s disease (HD) patients and can substantially impair their quality of life. Accumulating evidence suggests considerable dysfunction of the hypothalamic suprachiasmatic nucleus (SCN), the biological clock, in both HD patients and transgenic mouse mo...

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Detalles Bibliográficos
Autores principales:	Aziz, N. Ahmad, Pijl, Hanno, Frölich, Marijke, Schröder-van der Elst, Janny P., van der Bent, Chris, Roelfsema, Ferdinand, Roos, Raymund A. C.
Formato:	Texto
Lenguaje:	English
Publicado:	D. Steinkopff-Verlag 2009
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780627/ https://www.ncbi.nlm.nih.gov/pubmed/19562249 http://dx.doi.org/10.1007/s00415-009-5196-1

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