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Pparγ2 Is a Key Driver of Longevity in the Mouse

Aging involves a progressive physiological remodeling that is controlled by both genetic and environmental factors. Many of these factors impact also on white adipose tissue (WAT), which has been shown to be a determinant of lifespan. Interrogating a transcriptional network for predicted causal regu...

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Detalles Bibliográficos
Autores principales: Argmann, Carmen, Dobrin, Radu, Heikkinen, Sami, Auburtin, Aurélie, Pouilly, Laurent, Cock, Terrie-Anne, Koutnikova, Hana, Zhu, Jun, Schadt, Eric E., Auwerx, Johan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780700/
https://www.ncbi.nlm.nih.gov/pubmed/19997628
http://dx.doi.org/10.1371/journal.pgen.1000752