Cargando…

Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells

BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cytotoxicity against tumors, extremely limited information is so far available in humans on their capability of killing cancer cells in an autologous setting. METHODOLOGY/PRINCIPAL FINDINGS: We have est...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carrega, Paolo, Pezzino, Gaetana, Queirolo, Paola, Bonaccorsi, Irene, Falco, Michela, Vita, Giuseppe, Pende, Daniela, Misefari, Aldo, Moretta, Alessandro, Mingari, Maria Cristina, Moretta, Lorenzo, Ferlazzo, Guido
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780723/ https://www.ncbi.nlm.nih.gov/pubmed/19997637 http://dx.doi.org/10.1371/journal.pone.0008132

Ejemplares similares

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells
por: Locatelli, Franco, et al.
Publicado: (2013)

Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation
por: Pende, Daniela, et al.
Publicado: (2019)

Human NK Cells: From Surface Receptors to the Therapy of Leukemias and Solid Tumors
por: Moretta, Lorenzo, et al.
Publicado: (2014)

Human NK cells, their receptors and function [Image: see text]
por: Quatrini, Linda, et al.
Publicado: (2021)

Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
por: Ferlazzo, Guido, et al.
Publicado: (2002)

How melanoma cells inactivate NK cells
por: Pietra, Gabriella, et al.
Publicado: (2012)

Natural Killers Are Made Not Born: How to Exploit NK Cells in Lung Malignancies
por: Carrega, Paolo, et al.
Publicado: (2017)

NK cells from malignant pleural effusions are potent antitumor effectors: A clue for adoptive immunotherapy?
por: Vacca, Paola, et al.
Publicado: (2013)

An Historical Overview: The Discovery of How NK Cells Can Kill Enemies, Recruit Defense Troops, and More
por: Vitale, Massimo, et al.
Publicado: (2019)

Melanoma immunoediting by NK cells
por: Balsamo, Mirna, et al.
Publicado: (2012)

Heterogeneity of NK Cells and Other Innate Lymphoid Cells in Human and Murine Decidua
por: Vacca, Paola, et al.
Publicado: (2019)

NK Cell-Based Immunotherapy for Hematological Malignancies
por: Sivori, Simona, et al.
Publicado: (2019)

Exploiting Human NK Cells in Tumor Therapy
por: Vacca, Paola, et al.
Publicado: (2020)

NK Cells and Other Innate Lymphoid Cells in Hematopoietic Stem Cell Transplantation
por: Vacca, Paola, et al.
Publicado: (2016)

Symptomatic Carotid Atherosclerotic Plaques Are Associated With Increased Infiltration of Natural Killer (NK) Cells and Higher Serum Levels of NK Activating Receptor Ligands
por: Bonaccorsi, Irene, et al.
Publicado: (2019)

Natural killer cells: From surface receptors to the cure of high‐risk leukemia (Ceppellini Lecture)
por: Falco, Michela, et al.
Publicado: (2019)

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer
por: Sivori, Simona, et al.
Publicado: (2020)

Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia
por: Meazza, Raffaella, et al.
Publicado: (2020)

Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function
por: Manzini, Claudia, et al.
Publicado: (2016)

Effect of Tyrosin Kinase Inhibitors on NK Cell and ILC3 Development and Function
por: Damele, Laura, et al.
Publicado: (2018)

Characterization of KIR (+) NK cell subsets with a monoclonal antibody selectively recognizing KIR2DL1 and blocking the specific interaction with HLA‐C
por: Meazza, Raffaella, et al.
Publicado: (2022)

Dendritic Cell Editing by Activated Natural Killer Cells Results in a More Protective Cancer-Specific Immune Response
por: Morandi, Barbara, et al.
Publicado: (2012)

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?
por: Cantoni, Claudia, et al.
Publicado: (2016)

Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
por: Parodi, Monica, et al.
Publicado: (2018)

Licensed and Unlicensed NK Cells: Differential Roles in Cancer and Viral Control
por: Tu, Megan M., et al.
Publicado: (2016)

Drag cells in immunity: Plasmacytoid DCs dress up as cancer cells
por: Bonaccorsi, Irene, et al.
Publicado: (2014)

Stromal Cells from Human Decidua Exert a Strong Inhibitory Effect on NK Cell Function and Dendritic Cell Differentiation
por: Croxatto, Daniele, et al.
Publicado: (2014)

Impact of HCMV Infection on NK Cell Development and Function after HSCT
por: Della Chiesa, Mariella, et al.
Publicado: (2013)

Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor
por: Pesce, Silvia, et al.
Publicado: (2016)

KIR3DS1-Mediated Recognition of HLA-*B51: Modulation of KIR3DS1 Responsiveness by Self HLA-B Allotypes and Effect on NK Cell Licensing
por: Carlomagno, Simona, et al.
Publicado: (2017)

Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?
por: Della Chiesa, Mariella, et al.
Publicado: (2015)

Unique Eomes(+) NK Cell Subsets Are Present in Uterus and Decidua During Early Pregnancy
por: Montaldo, Elisa, et al.
Publicado: (2016)

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function
por: Stetson, Daniel B., et al.
Publicado: (2003)

NK Cell Precursors in Human Bone Marrow in Health and Inflammation
por: Bozzano, Federica, et al.
Publicado: (2019)

Cordycepin Sensitizes Cholangiocarcinoma Cells to Be Killed by Natural Killer-92 (NK-92) Cells
por: Panwong, Suthida, et al.
Publicado: (2021)

Naturally Killing the Silent Killer: NK Cell-Based Immunotherapy for Ovarian Cancer
por: Nersesian, Sarah, et al.
Publicado: (2019)

The tumor microenvironment drives NK cell metabolic dysfunction leading to impaired antitumor activity
por: Tumino, Nicola, et al.
Publicado: (2022)

In vivo evidence for dendritic cell lysis by NK cells: Hints on improving cancer vaccines by targeting NK cell activation
por: Ferlazzo, Guido
Publicado: (2012)

Human NK Cells and Herpesviruses: Mechanisms of Recognition, Response and Adaptation
por: Della Chiesa, Mariella, et al.
Publicado: (2019)

Natural killer cell distribution and trafficking in human tissues
por: Carrega, Paolo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_cav3vm4m009ougqmrqrhh3j8c5