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A Biophysical Model for Analysis of Transcription Factor Interaction and Binding Site Arrangement from Genome-Wide Binding Data

BACKGROUND: How transcription factors (TFs) interact with cis-regulatory sequences and interact with each other is a fundamental, but not well understood, aspect of gene regulation. METHODOLOGY/PRINCIPAL FINDINGS: We present a computational method to address this question, relying on the established...

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Detalles Bibliográficos
Autores principales: He, Xin, Chen, Chieh-Chun, Hong, Feng, Fang, Fang, Sinha, Saurabh, Ng, Huck-Hui, Zhong, Sheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780727/
https://www.ncbi.nlm.nih.gov/pubmed/19956545
http://dx.doi.org/10.1371/journal.pone.0008155