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A Biophysical Model for Analysis of Transcription Factor Interaction and Binding Site Arrangement from Genome-Wide Binding Data
BACKGROUND: How transcription factors (TFs) interact with cis-regulatory sequences and interact with each other is a fundamental, but not well understood, aspect of gene regulation. METHODOLOGY/PRINCIPAL FINDINGS: We present a computational method to address this question, relying on the established...
Autores principales: | He, Xin, Chen, Chieh-Chun, Hong, Feng, Fang, Fang, Sinha, Saurabh, Ng, Huck-Hui, Zhong, Sheng |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780727/ https://www.ncbi.nlm.nih.gov/pubmed/19956545 http://dx.doi.org/10.1371/journal.pone.0008155 |
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