Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

OBJECTIVE: The goal of this study was to characterize glycation adducts formed in both in vivo extracellular matrix (ECM) proteins of endoneurium from streptozotocin (STZ)-induced diabetic rats and in vitro by glycation of laminin and fibronectin with methylglyoxal and glucose. We also investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Duran-Jimenez, Beatriz, Dobler, Darin, Moffatt, Sarah, Rabbani, Naila, Streuli, Charles H., Thornalley, Paul J., Tomlinson, David R., Gardiner, Natalie J.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780874/
https://www.ncbi.nlm.nih.gov/pubmed/19720799
http://dx.doi.org/10.2337/db09-0320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780874/
https://www.ncbi.nlm.nih.gov/pubmed/19720799
http://dx.doi.org/10.2337/db09-0320

Ejemplares similares