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Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

OBJECTIVE: The goal of this study was to characterize glycation adducts formed in both in vivo extracellular matrix (ECM) proteins of endoneurium from streptozotocin (STZ)-induced diabetic rats and in vitro by glycation of laminin and fibronectin with methylglyoxal and glucose. We also investigated...

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Detalles Bibliográficos
Autores principales:	Duran-Jimenez, Beatriz, Dobler, Darin, Moffatt, Sarah, Rabbani, Naila, Streuli, Charles H., Thornalley, Paul J., Tomlinson, David R., Gardiner, Natalie J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780874/ https://www.ncbi.nlm.nih.gov/pubmed/19720799 http://dx.doi.org/10.2337/db09-0320

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