Cargando…

The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes

BACKGROUND: Gastrointestinal nematode (GIN) infection is one of the main constraints to sheep production both in temperate and tropical countries. Economic losses caused by GIN are related to decreased production, treatment costs and even animal death. The present paper was aimed at assessing the an...

Descripción completa

Detalles Bibliográficos
Autores principales: Cringoli, Giuseppe, Veneziano, Vincenzo, Mezzino, Laura, Morgoglione, Mariaelena, Pennacchio, Saverio, Rinaldi, Laura, Salamina, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780992/
https://www.ncbi.nlm.nih.gov/pubmed/19909507
http://dx.doi.org/10.1186/1746-6148-5-41
_version_ 1782174546848120832
author Cringoli, Giuseppe
Veneziano, Vincenzo
Mezzino, Laura
Morgoglione, Mariaelena
Pennacchio, Saverio
Rinaldi, Laura
Salamina, Vincenzo
author_facet Cringoli, Giuseppe
Veneziano, Vincenzo
Mezzino, Laura
Morgoglione, Mariaelena
Pennacchio, Saverio
Rinaldi, Laura
Salamina, Vincenzo
author_sort Cringoli, Giuseppe
collection PubMed
description BACKGROUND: Gastrointestinal nematode (GIN) infection is one of the main constraints to sheep production both in temperate and tropical countries. Economic losses caused by GIN are related to decreased production, treatment costs and even animal death. The present paper was aimed at assessing the anthelmintic efficacy (based on faecal egg count reduction) of moxidectin and ivermectin both admistered per os at dose rate of 0.2 mg/Kg body weight and the benefit of anthelmintic treatments on milk production in a commercial dairy sheep farms in central Italy whose animals were naturally infected by GIN. RESULTS: The treatment with moxidectin was highly effective (> 98%) from day 7 until day 75, and effective (90-98%) until day 105. The treatment with ivermectin was highly effective (> 98%) from day 7 until day 14, effective (90-98%) at day 28 and moderately effective (80-89%) on day 45. The milk productions in the treated groups were significantly higher than those of the control group. CONCLUSION: In conclusion, the results of the present study demonstrated that moxidectin and ivermectin adminstered per os according to the manufacturer's instructions were both effective and safe anthelmintics in sheep. The total milk production was higher in the treated groups than the control group. Overall, animals treated with moxidectin had a milk production 40.8% higher than control group; whereas animals treated with ivermectin had a milk production 32.2% higher than control group.
format Text
id pubmed-2780992
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-27809922009-11-24 The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes Cringoli, Giuseppe Veneziano, Vincenzo Mezzino, Laura Morgoglione, Mariaelena Pennacchio, Saverio Rinaldi, Laura Salamina, Vincenzo BMC Vet Res Research article BACKGROUND: Gastrointestinal nematode (GIN) infection is one of the main constraints to sheep production both in temperate and tropical countries. Economic losses caused by GIN are related to decreased production, treatment costs and even animal death. The present paper was aimed at assessing the anthelmintic efficacy (based on faecal egg count reduction) of moxidectin and ivermectin both admistered per os at dose rate of 0.2 mg/Kg body weight and the benefit of anthelmintic treatments on milk production in a commercial dairy sheep farms in central Italy whose animals were naturally infected by GIN. RESULTS: The treatment with moxidectin was highly effective (> 98%) from day 7 until day 75, and effective (90-98%) until day 105. The treatment with ivermectin was highly effective (> 98%) from day 7 until day 14, effective (90-98%) at day 28 and moderately effective (80-89%) on day 45. The milk productions in the treated groups were significantly higher than those of the control group. CONCLUSION: In conclusion, the results of the present study demonstrated that moxidectin and ivermectin adminstered per os according to the manufacturer's instructions were both effective and safe anthelmintics in sheep. The total milk production was higher in the treated groups than the control group. Overall, animals treated with moxidectin had a milk production 40.8% higher than control group; whereas animals treated with ivermectin had a milk production 32.2% higher than control group. BioMed Central 2009-11-12 /pmc/articles/PMC2780992/ /pubmed/19909507 http://dx.doi.org/10.1186/1746-6148-5-41 Text en Copyright ©2009 Cringoli et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research article
Cringoli, Giuseppe
Veneziano, Vincenzo
Mezzino, Laura
Morgoglione, Mariaelena
Pennacchio, Saverio
Rinaldi, Laura
Salamina, Vincenzo
The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title_full The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title_fullStr The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title_full_unstemmed The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title_short The effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
title_sort effect of moxidectin 0,1% vs ivermectin 0,08% on milk production in sheep naturally infected by gastrointestinal nematodes
topic Research article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780992/
https://www.ncbi.nlm.nih.gov/pubmed/19909507
http://dx.doi.org/10.1186/1746-6148-5-41
work_keys_str_mv AT cringoligiuseppe theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT venezianovincenzo theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT mezzinolaura theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT morgoglionemariaelena theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT pennacchiosaverio theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT rinaldilaura theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT salaminavincenzo theeffectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT cringoligiuseppe effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT venezianovincenzo effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT mezzinolaura effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT morgoglionemariaelena effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT pennacchiosaverio effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT rinaldilaura effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes
AT salaminavincenzo effectofmoxidectin01vsivermectin008onmilkproductioninsheepnaturallyinfectedbygastrointestinalnematodes