Combined Anti-Angiogenic Therapy Targeting PDGF and VEGF Receptors Lowers the Interstitial Fluid Pressure in a Murine Experimental Carcinoma

Elevation of the interstitial fluid pressure (IFP) of carcinoma is an obstacle in treatment of tumors by chemotherapy and correlates with poor drug uptake. Previous studies have shown that treatment with inhibitors of platelet-derived growth factor (PDGF) or vascular endothelial growth factor (VEGF)...

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Detalles Bibliográficos
Autores principales: Kłosowska-Wardęga, Agnieszka, Hasumi, Yoko, Burmakin, Mikhail, Åhgren, Aive, Stuhr, Linda, Moen, Ingrid, Reed, Rolf K., Rubin, Kristofer, Hellberg, Carina, Heldin, Carl-Henrik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781164/
https://www.ncbi.nlm.nih.gov/pubmed/19997591
http://dx.doi.org/10.1371/journal.pone.0008149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781164/
https://www.ncbi.nlm.nih.gov/pubmed/19997591
http://dx.doi.org/10.1371/journal.pone.0008149

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