Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis

BACKGROUND: Dissociating glucocorticoid receptor (GR) ligands hold great promise for treating inflammatory disorders since it is assumed that they exert beneficial activities mediated by transrepression but avoid adverse effects of GR action requiring transactivation. Here we challenged this paradig...

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Detalles Bibliográficos
Autores principales: Wüst, Simone, Tischner, Denise, John, Michael, Tuckermann, Jan P., Menzfeld, Christiane, Hanisch, Uwe-Karsten, van den Brandt, Jens, Lühder, Fred, Reichardt, Holger M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781169/
https://www.ncbi.nlm.nih.gov/pubmed/19997594
http://dx.doi.org/10.1371/journal.pone.0008202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781169/
https://www.ncbi.nlm.nih.gov/pubmed/19997594
http://dx.doi.org/10.1371/journal.pone.0008202

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