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Comprehensive Functional Analysis of Mycobacterium tuberculosis Toxin-Antitoxin Systems: Implications for Pathogenesis, Stress Responses, and Evolution

Toxin-antitoxin (TA) systems, stress-responsive genetic elements ubiquitous in microbial genomes, are unusually abundant in the major human pathogen Mycobacterium tuberculosis. Why M. tuberculosis has so many TA systems and what role they play in the unique biology of the pathogen is unknown. To add...

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Detalles Bibliográficos
Autores principales:	Ramage, Holly R., Connolly, Lynn E., Cox, Jeffery S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781298/ https://www.ncbi.nlm.nih.gov/pubmed/20011113 http://dx.doi.org/10.1371/journal.pgen.1000767

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