Simple Sequence Repeats and Mucoid Conversion: Biased mucA Mutagenesis in Mismatch Repair-Deficient Pseudomonas aeruginosa

In Pseudomonas aeruginosa, conversion to the mucoid phenotype marks the onset of an irreversible state of the infection in Cystic Fibrosis (CF) patients. The main pathway for mucoid conversion is mutagenesis of the mucA gene, frequently due to −1 bp deletions in a simple sequence repeat (SSR) of 5 G...

Descripción completa

Detalles Bibliográficos
Autores principales: Moyano, Alejandro J., Smania, Andrea M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781719/
https://www.ncbi.nlm.nih.gov/pubmed/19997602
http://dx.doi.org/10.1371/journal.pone.0008203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781719/
https://www.ncbi.nlm.nih.gov/pubmed/19997602
http://dx.doi.org/10.1371/journal.pone.0008203

Ejemplares similares