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Efficiently finding genome-wide three-way gene interactions from transcript- and genotype-data

Motivation: We address the issue of finding a three-way gene interaction, i.e. two interacting genes in expression under the genotypes of another gene, given a dataset in which expressions and genotypes are measured at once for each individual. This issue can be a general, switching mechanism in exp...

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Detalles Bibliográficos
Autores principales: Kayano, Mitsunori, Takigawa, Ichigaku, Shiga, Motoki, Tsuda, Koji, Mamitsuka, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781753/
https://www.ncbi.nlm.nih.gov/pubmed/19736252
http://dx.doi.org/10.1093/bioinformatics/btp531