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Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer
BACKGROUND: Increase of EGFR gene copy number consequent to gene amplification and/or polysomy of chromosome 7 has been significantly associated with better clinical outcome in Non Small Cell Lung Cancer (NSCLC) patients treated with Tyrosin-Kinase Inhibitors (TKIs). The primary method to detect EGF...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781797/ https://www.ncbi.nlm.nih.gov/pubmed/19889201 http://dx.doi.org/10.1186/1746-1596-4-36 |