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Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer

BACKGROUND: Increase of EGFR gene copy number consequent to gene amplification and/or polysomy of chromosome 7 has been significantly associated with better clinical outcome in Non Small Cell Lung Cancer (NSCLC) patients treated with Tyrosin-Kinase Inhibitors (TKIs). The primary method to detect EGF...

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Detalles Bibliográficos
Autores principales: Casorzo, Laura, Corigliano, Mara, Ferrero, Paolo, Venesio, Tiziana, Risio, Mauro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781797/
https://www.ncbi.nlm.nih.gov/pubmed/19889201
http://dx.doi.org/10.1186/1746-1596-4-36

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