FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures

In this study, we report that the purified wild-type FANCI (Fanconi anemia complementation group I) protein directly binds to a variety of DNA substrates. The DNA binding domain roughly encompasses residues 200–1000, as suggested by the truncation study. When co-expressed in insect cells, a small fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Fenghua, El Hokayem, Jimmy, Zhou, Wen, Zhang, Yanbin
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782037/
https://www.ncbi.nlm.nih.gov/pubmed/19561358
http://dx.doi.org/10.1074/jbc.M109.016006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782037/
https://www.ncbi.nlm.nih.gov/pubmed/19561358
http://dx.doi.org/10.1074/jbc.M109.016006

Ejemplares similares