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FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures

In this study, we report that the purified wild-type FANCI (Fanconi anemia complementation group I) protein directly binds to a variety of DNA substrates. The DNA binding domain roughly encompasses residues 200–1000, as suggested by the truncation study. When co-expressed in insect cells, a small fr...

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Detalles Bibliográficos
Autores principales:	Yuan, Fenghua, El Hokayem, Jimmy, Zhou, Wen, Zhang, Yanbin
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782037/ https://www.ncbi.nlm.nih.gov/pubmed/19561358 http://dx.doi.org/10.1074/jbc.M109.016006

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