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Epigallocatechin-3-gallate Suppresses Galactose-α1,4-galactose-β1,4-glucose Ceramide Expression in TNF-α Stimulated Human Intestinal Epithelial Cells Through Inhibition of MAPKs and NF-κB

Intestinal epithelial cells (IECs) have been known to produce galactose-α1,4-galactose-β1,4-glucose ceramide (Gb3) that play an important role in the mucosal immune response. The regulation of Gb3 is important to prevent tissue damage causing shiga like toxin. Epigallocatechin-3-gallate (EGCG) has b...

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Detalles Bibliográficos
Autores principales: Moon, Dong-Oh, Choi, Se-Rim, Lee, Chang-Min, Kim, Gi-Young, Lee, Hee-Jeong, Park, Yeong-Min
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782146/
https://www.ncbi.nlm.nih.gov/pubmed/16100442
http://dx.doi.org/10.3346/jkms.2005.20.4.548