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Extraskeletal Ewing's Sarcoma of the Hard Palate
Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal d...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782172/ https://www.ncbi.nlm.nih.gov/pubmed/16100468 http://dx.doi.org/10.3346/jkms.2005.20.4.687 |
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author | Kang, Mi Seon Yoon, Hye Kyoung Choi, Jung Bae Eum, Jae Wook |
author_facet | Kang, Mi Seon Yoon, Hye Kyoung Choi, Jung Bae Eum, Jae Wook |
author_sort | Kang, Mi Seon |
collection | PubMed |
description | Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction. |
format | Text |
id | pubmed-2782172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-27821722009-11-25 Extraskeletal Ewing's Sarcoma of the Hard Palate Kang, Mi Seon Yoon, Hye Kyoung Choi, Jung Bae Eum, Jae Wook J Korean Med Sci Case Report Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction. The Korean Academy of Medical Sciences 2005-08 2005-08-31 /pmc/articles/PMC2782172/ /pubmed/16100468 http://dx.doi.org/10.3346/jkms.2005.20.4.687 Text en Copyright © 2005 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kang, Mi Seon Yoon, Hye Kyoung Choi, Jung Bae Eum, Jae Wook Extraskeletal Ewing's Sarcoma of the Hard Palate |
title | Extraskeletal Ewing's Sarcoma of the Hard Palate |
title_full | Extraskeletal Ewing's Sarcoma of the Hard Palate |
title_fullStr | Extraskeletal Ewing's Sarcoma of the Hard Palate |
title_full_unstemmed | Extraskeletal Ewing's Sarcoma of the Hard Palate |
title_short | Extraskeletal Ewing's Sarcoma of the Hard Palate |
title_sort | extraskeletal ewing's sarcoma of the hard palate |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782172/ https://www.ncbi.nlm.nih.gov/pubmed/16100468 http://dx.doi.org/10.3346/jkms.2005.20.4.687 |
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