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Extraskeletal Ewing's Sarcoma of the Hard Palate

Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal d...

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Detalles Bibliográficos
Autores principales: Kang, Mi Seon, Yoon, Hye Kyoung, Choi, Jung Bae, Eum, Jae Wook
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782172/
https://www.ncbi.nlm.nih.gov/pubmed/16100468
http://dx.doi.org/10.3346/jkms.2005.20.4.687
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author Kang, Mi Seon
Yoon, Hye Kyoung
Choi, Jung Bae
Eum, Jae Wook
author_facet Kang, Mi Seon
Yoon, Hye Kyoung
Choi, Jung Bae
Eum, Jae Wook
author_sort Kang, Mi Seon
collection PubMed
description Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction.
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spelling pubmed-27821722009-11-25 Extraskeletal Ewing's Sarcoma of the Hard Palate Kang, Mi Seon Yoon, Hye Kyoung Choi, Jung Bae Eum, Jae Wook J Korean Med Sci Case Report Extraskeletal Ewing's sarcoma (EES) is a rare soft tissue tumor morphologically indistinguishable from the more common Ewing's sarcoma of bone. We report a case of EES arising in the hard palate of 34-yr-old male patient. Microscopically, the monotonous small round cells without neuronal differentiation showed membranous positive immunoreactivity for MIC2/CD99 and vimentin. Ultrastructurally, the tumor cells showed a few intracytoplasmic organelles without evidence of neurosecretory granules or neurofilaments. The EWS-FLI1 chimeric gene was identified using the nested reverse transcriptase-polymerase chain reaction. The Korean Academy of Medical Sciences 2005-08 2005-08-31 /pmc/articles/PMC2782172/ /pubmed/16100468 http://dx.doi.org/10.3346/jkms.2005.20.4.687 Text en Copyright © 2005 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kang, Mi Seon
Yoon, Hye Kyoung
Choi, Jung Bae
Eum, Jae Wook
Extraskeletal Ewing's Sarcoma of the Hard Palate
title Extraskeletal Ewing's Sarcoma of the Hard Palate
title_full Extraskeletal Ewing's Sarcoma of the Hard Palate
title_fullStr Extraskeletal Ewing's Sarcoma of the Hard Palate
title_full_unstemmed Extraskeletal Ewing's Sarcoma of the Hard Palate
title_short Extraskeletal Ewing's Sarcoma of the Hard Palate
title_sort extraskeletal ewing's sarcoma of the hard palate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782172/
https://www.ncbi.nlm.nih.gov/pubmed/16100468
http://dx.doi.org/10.3346/jkms.2005.20.4.687
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