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Integrin Clustering Is Driven by Mechanical Resistance from the Glycocalyx and the Substrate
Integrins have emerged as key sensory molecules that translate chemical and physical cues from the extracellular matrix (ECM) into biochemical signals that regulate cell behavior. Integrins function by clustering into adhesion plaques, but the molecular mechanisms that drive integrin clustering in r...
Autores principales: | Paszek, Matthew J., Boettiger, David, Weaver, Valerie M., Hammer, Daniel A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782178/ https://www.ncbi.nlm.nih.gov/pubmed/20011123 http://dx.doi.org/10.1371/journal.pcbi.1000604 |
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