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8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist

cADPR (cyclic ADP-ribose) is a universal Ca(2+) mobilizing second messenger. In T-cells cADPR is involved in sustained Ca(2+) release and also in Ca(2+) entry. Potential mechanisms for the latter include either capacitative Ca(2+) entry, secondary to store depletion by cADPR, or direct activation of...

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Detalles Bibliográficos
Autores principales:	Kirchberger, Tanja, Moreau, Christelle, Wagner, Gerd K., Fliegert, Ralf, Siebrands, Cornelia C., Nebel, Merle, Schmid, Frederike, Harneit, Angelika, Odoardi, Francesca, Flügel, Alexander, Potter, Barry V. L., Guse, Andreas H.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782309/ https://www.ncbi.nlm.nih.gov/pubmed/19492987 http://dx.doi.org/10.1042/BJ20082308

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