Mechanism of Glycan Receptor Recognition and Specificity Switch for Avian, Swine, and Human Adapted Influenza Virus Hemagglutinins: A Molecular Dynamics Perspective

[Image: see text] Hemagglutinins (HA’s) from duck, swine, and human influenza viruses have previously been shown to prefer avian and human glycan receptor analogues with distinct topological profiles, pentasaccharides LSTa (α-2,3 linkage) and LSTc (α-2,6 linkage), in comparative molecular dynamics s...

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Detalles Bibliográficos
Autores principales: Newhouse, E. Irene, Xu, Dong, Markwick, Phineus R. L., Amaro, Rommie E., Pao, Hsing C., Wu, Kevin J., Alam, Maqsudul, McCammon, J. Andrew, Li, Wilfred W.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782351/
https://www.ncbi.nlm.nih.gov/pubmed/19891427
http://dx.doi.org/10.1021/ja904052q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782351/
https://www.ncbi.nlm.nih.gov/pubmed/19891427
http://dx.doi.org/10.1021/ja904052q

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