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Mechanism of Glycan Receptor Recognition and Specificity Switch for Avian, Swine, and Human Adapted Influenza Virus Hemagglutinins: A Molecular Dynamics Perspective
[Image: see text] Hemagglutinins (HA’s) from duck, swine, and human influenza viruses have previously been shown to prefer avian and human glycan receptor analogues with distinct topological profiles, pentasaccharides LSTa (α-2,3 linkage) and LSTc (α-2,6 linkage), in comparative molecular dynamics s...
Autores principales: | Newhouse, E. Irene, Xu, Dong, Markwick, Phineus R. L., Amaro, Rommie E., Pao, Hsing C., Wu, Kevin J., Alam, Maqsudul, McCammon, J. Andrew, Li, Wilfred W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782351/ https://www.ncbi.nlm.nih.gov/pubmed/19891427 http://dx.doi.org/10.1021/ja904052q |
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