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Integrin α8β1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism
Background. Integrins are transmembrane αβ heterodimer receptors that function as structural and functional bridges between the cytoskeleton and ECM (extracellular matrix) molecules. The RGD (arginine-glycine-aspartate tripeptide motif)-dependent integrin α8β1 has been shown to be involved in variou...
Autores principales: | Benoit, Yannick D., Lussier, Carine, Ducharme, Pierre-Alexandre, Sivret, Sophie, Schnapp, Lynn M., Basora, Nuria, Beaulieu, Jean-François |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782361/ https://www.ncbi.nlm.nih.gov/pubmed/19527220 http://dx.doi.org/10.1042/BC20090060 |
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