Global variation in CYP2C8–CYP2C9 functional haplotypes

We have studied the global frequency distributions of 10 single nucleotide polymorphisms (SNPs) across 132 kb of CYP2C8 and CYP2C9 in ∼2500 individuals representing 45 populations. Five of the SNPs were in noncoding sequences; the other five involved the more common missense variants (four in CYP2C8...

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Detalles Bibliográficos
Autores principales: Speed, William C, Kang, Soonmo Peter, Tuck, David P, Harris, Lyndsay N, Kidd, Kenneth K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782405/
https://www.ncbi.nlm.nih.gov/pubmed/19381162
http://dx.doi.org/10.1038/tpj.2009.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782405/
https://www.ncbi.nlm.nih.gov/pubmed/19381162
http://dx.doi.org/10.1038/tpj.2009.10

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