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Global variation in CYP2C8–CYP2C9 functional haplotypes
We have studied the global frequency distributions of 10 single nucleotide polymorphisms (SNPs) across 132 kb of CYP2C8 and CYP2C9 in ∼2500 individuals representing 45 populations. Five of the SNPs were in noncoding sequences; the other five involved the more common missense variants (four in CYP2C8...
Autores principales: | Speed, William C, Kang, Soonmo Peter, Tuck, David P, Harris, Lyndsay N, Kidd, Kenneth K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782405/ https://www.ncbi.nlm.nih.gov/pubmed/19381162 http://dx.doi.org/10.1038/tpj.2009.10 |
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