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SSB diffusion on single stranded DNA stimulates RecA filament formation

Single stranded (ss)DNA generated in the cell during DNA metabolism is stabilized and protected by binding of single stranded DNA binding (SSB) proteins. E. coli SSB, a representative homotetrameric SSB, binds to ssDNA by wrapping the DNA using its four subunits. However, such a tightly wrapped, hig...

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Detalles Bibliográficos
Autores principales: Roy, Rahul, Kozlov, Alexander G., Lohman, Timothy M., Ha, Taekjip
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782680/
https://www.ncbi.nlm.nih.gov/pubmed/19820696
http://dx.doi.org/10.1038/nature08442