Cargando…

Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours

Current hormonal therapies for prostate cancer are effective initially, but inevitably tumours progress to an advanced, metastatic stage, often referred to as ‘androgen independent’. However, the androgen receptor (AR) signalling pathway is still key for their growth. It is speculated that tumours e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dart, D Alwyn, Spencer-Dene, Bradley, Gamble, Simon C, Waxman, Jonathan, Bevan, Charlotte L
Formato:	Texto
Lenguaje:	English
Publicado:	Society for Endocrinology 2009
Materias:	Regular Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782800/ https://www.ncbi.nlm.nih.gov/pubmed/19635783 http://dx.doi.org/10.1677/ERC-09-0028

Ejemplares similares

Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens
por: Dart, D. A., et al.
Publicado: (2011)

Visualising Androgen Receptor Activity in Male and Female Mice
por: Dart, D. Alwyn, et al.
Publicado: (2013)

The prohibitin-repressive interaction with E2F1 is rapidly inhibited by androgen signalling in prostate cancer cells
por: Koushyar, S, et al.
Publicado: (2017)

Prohibitin Links Cell Cycle, Motility and Invasion in Prostate Cancer Cells
por: Koushyar, Sarah, et al.
Publicado: (2023)

Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells
por: Brooke, Greg N., et al.
Publicado: (2015)

Androgen resistance in prostate cancer
por: Waxman, J, et al.
Publicado: (2008)

Enhancement of chemotherapy by manipulation of tumour pH
por: Raghunand, N, et al.
Publicado: (1999)

Optimal timing and dosage of chemotherapy as a combined treatment with androgen withdrawal in the human prostate LNCaP tumour model
por: Miyake, H, et al.
Publicado: (2001)

Regulation of expression of Na(+),K(+)-ATPase in androgen-dependent and androgen-independent prostate cancer
por: Blok, L J, et al.
Publicado: (1999)

Switch from antagonist to agonist of the androgen receptor blocker bicalutamide is associated with prostate tumour progression in a new model system
por: Culig, Z, et al.
Publicado: (1999)

Prostate cancer treated by anti-androgens: is sexual function preserved?
por: Schröder, F H, et al.
Publicado: (2000)

Androgen Receptor Signalling in Prostate Cancer: The Functional Consequences of Acetylation
por: Lavery, Derek N., et al.
Publicado: (2011)

Prohibitin-1 Transgenic Mice Revealed an Important Role of Prohibitin in Testicular Steroidogenesis
por: Bassi, Geetika, et al.
Publicado: (2021)

Circulating microRNAs as potential new biomarkers for prostate cancer
por: Sita-Lumsden, A, et al.
Publicado: (2013)

In vivo fluorescence imaging of the transport of charged chlorine6 conjugates in a rat orthotopic prostate tumour
por: Hamblin, M R, et al.
Publicado: (1999)

Expression and regulation of prostate androgen regulated transcript-1 (PART-1) and identification of differential expression in prostatic cancer
por: Sidiropoulos, M, et al.
Publicado: (2001)

Prohibitins in neurodegeneration and mitochondrial homeostasis
por: Fernandez-Abascal, Jesus, et al.
Publicado: (2022)

Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer
por: Fletcher, Claire E., et al.
Publicado: (2019)

Cellular specificity of androgen receptor, coregulators, and pioneer factors in prostate cancer
por: Leach, Damien A, et al.
Publicado: (2022)

Camptothecin sensitizes androgen-independent prostate cancer cells to anti-Fas-induced apoptosis
por: Costa-Pereira, A P, et al.
Publicado: (1999)

Engineered repressors are potent inhibitors of androgen receptor activity
por: Brooke, Greg N., et al.
Publicado: (2014)

Androgen receptor protein is down-regulated by basic fibroblast growth factor in prostate cancer cells
por: Cronauer, M V, et al.
Publicado: (2000)

CAG repeat length in the androgen receptor gene is related to age at diagnosis of prostate cancer and response to endocrine therapy, but not to prostate cancer risk
por: Bratt, O, et al.
Publicado: (1999)

Eighty Years of Targeting Androgen Receptor Activity in Prostate Cancer: The Fight Goes on
por: Estébanez-Perpiñá, Eva, et al.
Publicado: (2021)

Opposing function of mitochondrial prohibitin in aging
por: Artal-Sanz, Marta, et al.
Publicado: (2010)

The Prohibitins: emerging roles in diverse functions
por: Mishra, Suresh, et al.
Publicado: (2006)

The function of prohibitins in mitochondria and the clinical potentials
por: Oyang, Linda, et al.
Publicado: (2022)

Tumour cells engineered to secrete interleukin-15 augment anti-tumour immune responses in vivo
por: Hazama, S, et al.
Publicado: (1999)

Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis
por: Costa-Pereira, A P, et al.
Publicado: (2000)

mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer
por: Schiewer, Matthew J, et al.
Publicado: (2012)

CaMK IV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription
por: Sun, Luguo, et al.
Publicado: (2011)

The Role of Androgen Receptor Mutations in Prostate Cancer Progression
por: Brooke, G.N, et al.
Publicado: (2009)

In vivo isolated kidney perfusion with tumour necrosis factor α (TNF-α) in tumour-bearing rats
por: Veen, A H van der, et al.
Publicado: (1999)

Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways
por: Oh, Su Jung, et al.
Publicado: (2012)

Involvement of Prohibitin Upregulation in Abrin-Triggered Apoptosis
por: Liu, Yu-Huei, et al.
Publicado: (2012)

Prohibitins Are Required for Cancer Cell Proliferation and Adhesion
por: Sievers, Claudia, et al.
Publicado: (2010)

Multifaceted role of prohibitin in cell survival and apoptosis
por: Peng, Ya-Ting, et al.
Publicado: (2015)

Prohibitin as a novel autoantigen in rheumatoid arthritis
por: Shi, Li-Li, et al.
Publicado: (2015)

Prohibitin: an unexpected role in sex dimorphic functions
por: Nguyen, K. Hoa, et al.
Publicado: (2016)

Proteomic Changes in Rat Spermatogenesis in Response to In Vivo Androgen Manipulation; Impact on Meiotic Cells
por: Stanton, Peter G., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_kkeim2vuv3ieqf278r58jtcfec