A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides

BACKGROUND: Developing methods for understanding the connectivity of signalling pathways is a major challenge in biological research. For this purpose, mathematical models are routinely developed based on experimental observations, which also allow the prediction of the system behaviour under differ...

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Detalles Bibliográficos
Autores principales: Roberts, Mark AJ, August, Elias, Hamadeh, Abdullah, Maini, Philip K, McSharry, Patrick E, Armitage, Judith P, Papachristodoulou, Antonis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783038/
https://www.ncbi.nlm.nih.gov/pubmed/19878602
http://dx.doi.org/10.1186/1752-0509-3-105

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